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Trimethylglycine – TMG betaine

Brad Stanfield:500mg
Siim Land:1000 mg
Serge Faguet:Dosage Unknown
David Sinclair:500-1,000 mg
Dave Pascoe:3,000 mg
Bryan Johnson:Dosage Unknown

TMG, or trimethylglycine, is also known as betaine. It is a naturally occurring compound found in various foods, such as beets, spinach, and whole grains. Betaine supplements are used for several potential health benefits, including:

  1. Support for Methylation: Betaine is involved in methylation, a biochemical process that affects many bodily functions, including DNA synthesis and repair. It helps donate methyl groups to various biochemical reactions, which is important for maintaining cellular health.
  2. Liver Health: Betaine is often used to support liver function. It has been studied for its potential to reduce liver fat and improve conditions like non-alcoholic fatty liver disease (NAFLD).
  3. Homocysteine Levels: Betaine may help lower homocysteine levels, an amino acid linked to an increased risk of cardiovascular disease when elevated. By supporting healthy homocysteine metabolism, betaine might contribute to heart health.
  4. Athletic Performance: Some studies suggest that betaine supplementation may enhance exercise performance and increase muscle strength and power, although results can vary.
  5. Digestive Health: Betaine hydrochloride (a form of betaine) is sometimes used to support digestive health by increasing stomach acid production, which can aid in digestion and absorption of nutrients.

TMG supplements are generally available in capsule, powder, or tablet form. As with any supplement, it’s important to consult with a healthcare provider before starting betaine, especially if you have any underlying health conditions or are taking other medications.